Bill Gates, co-founder of Microsoft, has voiced strong concerns regarding the accelerating pace of AI development, particularly noting that "guardrails are not keeping pace." In a recent essay and interview, Gates stated that humanity has already "crossed the threshold" for multiple potential dangers, specifically citing bio-capabilities, cyber-capabilities, psychosocial capabilities, job-market destruction capabilities, and hints of crossing the control threshold. He emphasized his astonishment at the "lack of concern and discussion outside of the industry" regarding these issues, advocating for monitoring of AI models that can create new molecules and suggesting international agreements with countries like China to manage these risks.

Gates highlighted three primary risks: massive job displacement, empowered criminals, and stunted child development. He predicts that many entry-level white-collar jobs, such as customer support, software engineering, and paralegal work, will disappear, and that blue-collar jobs in construction and hospitality will see significant automation by the end of the decade. Gates also warned that AI could enable criminals to execute fraud, disinformation campaigns, and deepfakes more effectively, and could facilitate bioterrorism by making it easier to design deadly new diseases. Furthermore, he expressed concern that AI companions could be highly addictive for children, potentially hindering the development of social skills and human relationships.

While acknowledging AI's potential benefits in healthcare, education, and government efficiency, Gates called for immediate action from governments to establish new institutions and frameworks. He proposed solutions such as a "token tax" on AI use to make replacing human workers more costly and to fund support for displaced individuals. Gates also advocated for new international agreements to monitor and restrict extreme risks like bioterrorism. However, some experts, like computer science professor Oren Etzioni, agreed with Gates' diagnosis but questioned his proposed "token tax," arguing it might measure effort rather than displacement and could hinder U.S. competitiveness if other nations don't adopt similar measures.