The ongoing conflict with Iran has led to a substantial depletion of the United States' stockpiles of critical missile interceptors. According to internal Pentagon reports, the US military has expended nearly 80% of its THAAD missile inventory and approximately half of its Patriot interceptors since the war's commencement. Before the war, the Center for Strategic and International Studies (CSIS) estimated the US held around 2,200 Patriot missiles (of the two most modern variants) and 452 THAAD missiles. Current estimates by CSIS, which align with internal government figures, suggest fewer than 827 Patriot and fewer than 278 THAAD interceptors remain.

This rapid depletion of air defense systems is forcing the US and its allies to consider taking increased risks in interception strategies. Analysts from CSIS highlight that there are no viable alternatives to Patriot and THAAD for ballistic missile defense, and naval assets equipped with Standard Missiles are often too distant to be effective. Concerns have been raised that diminished stockpiles might necessitate changes in military doctrine, such as reducing the number of interceptors fired at incoming threats, thereby increasing the risk of successful strikes.

The financial implications of the conflict are also significant. Defense Secretary Pete Hegseth reported that the war has cost an estimated $37.5 billion. The Pentagon is currently seeking an additional $67 billion from Congress to replenish its military arsenal, including high-end munitions like Patriot and THAAD interceptors. This situation underscores a broader concern about the sustainability of US military operations and its ability to maintain effective defense capabilities amidst prolonged engagement.